CD19 antibody

Catalog No. ABIN969015

This anti-CD19 antibody is a Mouse Monoclonal antibody detecting CD19 in FACS, ELISA and ICC. Suitable for Human. This Primary Antibody has been cited in 1 publication.

Quick Overview for CD19 antibody (ABIN969015)

Target: CD19 (CD19 Molecule (CD19))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD19 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)

Clone: 2E2

Product Details anti-CD19 Antibody

Purpose: CD19 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human CD19 expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD19 antibody (ABIN969015)

de Rie, Zeijlemaker, von dem Borne: "Inhibition, by vinca alkaloids and colchicine, of antigenic modulation induced by anti-CD19 monoclonal antibodies." in: Leukemia research, Vol. 12, Issue 2, pp. 135-41, (1988) (PubMed).

Target Details for CD19

Target: CD19 (CD19 Molecule (CD19))

Alternative Name: CD19

Background: The CD19 antigen (95 kDa) is expressed from the earliest stage of B progenitor development, on all peripheral B cells including germinal centre B cells, and all B cell lines and B cell leukaemia tested. T cell and monocytic cell lines are negative and the antigen is lost on B cell maturation to plasma cells. The antigen is a type I integral membrane glycoprotein whose in vitro inhibition will influence B cell activation and proliferation.

Molecular Weight: 61 kDa

UniProt: P15391

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway